Key Highlights
- Wegovy is a once-weekly injection approved by Health Canada
- It should be injected into the abdomen, thigh, or upper arm.
- Each pen is prefilled for single use, with doses increasing from 0.25 mg up to 2.4 mg as prescribed.
- You can inject Wegovy at any time of day. Just stick to the same day each week for the best results.
- If a dose is missed and it’s been fewer than 5 days, take your next weekly dose as soon as possible. If it’s been more than 5 days, skip it and resume your regular schedule.
- Store Wegovy pens in the refrigerator (36°F to 46°F / 2°C to 8°C). Do not freeze. Room temperature storage (up to 86°F or 30°C) is allowed for up to 28 days.
- DooÜ offers online assessments, licensed prescriptions, home delivery, and ongoing support to help you stay on track with Wegovy.
If you’re new to Wegovy, the idea of giving yourself a weekly injection can feel intimidating, but it doesn’t have to be. With proper technique, preparation, and a bit of confidence, administering your dose becomes simple, safe, and surprisingly quick.
Understanding how to use the pen correctly is important for anyone using Wegovy as part of a healthcare-guided plan.
In this blog, we’ll walk you through where and how to inject Wegovy safely, provide step-by-step instructions, and share practical tips to make your experience smoother and stress-free.
What Is Wegovy?

Wegovy is a Health Canada-approved prescription medication for adults under supervision. It contains Semaglutide, a compound that mimics the natural hormone GLP-1, which helps regulate appetite, food intake, and blood sugar levels.
By acting like GLP-1 (glucagon-like peptide-1), Wegovy is taken once a week as a subcutaneous injection. It works in conjunction with a reduced calorie diet and regular physical activity to support body weight management by influencing appetite and food intake.
Where to Inject Wegovy?
There are three recommended areas by Novo Nordisk where you can safely and effectively inject: the abdomen, thigh, and the upper arm. Each of these sites is equally effective, so you can choose the one that fits best with your routine and comfort level.
To help your body absorb the medication properly and to prevent irritation, it’s important to rotate your injection spots each week, even within the same area. For example, alternate between the left and right thigh or use different parts of your abdomen.
Curious if Wegovy is right for you?
How To Inject Wegovy Safely?

Now that you know where to inject Wegovy, let’s go over how to inject Wegovy step by step for the abdomen, thigh, and upper arm. Once you get the hang of it, it will feel like second nature.
1. Abdomen Injection
Injecting Wegovy into the abdomen is considered the best place to inject Wegovy, because it’s easy to reach and is comfortable as compared to the thighs and arms. If you're wondering how to inject Wegovy in stomach, follow these steps for safe administration:
- Choose a spot at least 2 inches away from your belly button, avoiding bruised or scarred skin.
- Clean the area with soap and water or an alcohol swab, and let it dry.
- Stand or sit, press the pen straight against the skin, and inject. Wait for the yellow bar to stop moving before removing the pen.
Injection Tips for Comfort:
Rotate spots weekly to avoid irritation. Standing can help tighten the skin for a smoother injection. This is especially helpful if you’re also monitoring other symptoms of low blood sugar or changes in heart rate.
2. Thigh Injection
The front of the upper thigh is another excellent injection site, especially for those self‑administering. Here’s where to inject Wegovy in leg and how to do it correctly:
- Use the front of your upper thigh, around the middle of the thigh area.
- Sit down to relax the muscle, clean the area, and let it dry.
- Inject by holding the pen firmly against the skin until the yellow bar stops.
Injection Tips for Comfort:
Alternate thighs or vary spots to prevent irritation. Sitting makes the process steadier and more comfortable.
Be mindful if you're also taking other medications or herbal supplements that may interact with Semaglutide or influence the negative side effects of prescription drugs.
3. Upper Arm Injection
The outer or back of the upper arm is the third recommended site for Wegovy injections. This area is often best if you have someone to assist you, as self‑injecting in the upper arm can be difficult.
- Choose the outer or back part of your upper arm.
- Clean and dry the skin.
- Have someone press the pen firmly at a 90-degree angle and hold it until the yellow bar finishes moving.
Injection Tips for Comfort:
Switch arms weekly. Make sure the injection goes into the fatty layer under the skin, not into the muscle. Injecting into the muscle can increase discomfort and may interfere with how the body absorbs this receptor agonist medication.
If you're asking yourself, what is the trick to the injection? Well, it's all about consistency, rotating injection sites, reading the medication guide properly, and giving yourself time to get comfortable with the process.
When and How to Take Your Wegovy Dose?

First of all, how many doses are in a Wegovy pen? So, the Wegovy pen contains one prefilled dose and is designed for single use only. As your treatment progresses, the dosage typically increases in specific steps: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg.
So, how often do you inject Wegovy? Wegovy is a once‑weekly injection, and the best time of the day to inject Wegovy is whenever it fits comfortably into your schedule. There is no strict requirement to inject in the morning, afternoon, or evening, but what matters most is consistency. Pick a day and stick to it each week, as this helps maintain the medication's effectiveness.
You can take Wegovy with or without food, so your chance of food intake doesn't influence the timing. Many people prefer a day and time they can easily remember, such as a quiet weekend morning or an evening after work.
If you ever experience mild nausea, which can sometimes occur due to loss of fluids, injecting in the evening can make it easier to sleep through any discomfort.
If you miss a dose and the next scheduled dose is more than 2 days away (48 hours), take the missed dose as soon as possible. If you miss a dose and the next scheduled dose is less than 2 days away (48 hours), do not administer the dose. Take your next dose on the regularly scheduled day.
This protocol helps avoid the risk of low blood sugar, especially for those already managing type 2 diabetes or those with endocrine neoplasia syndrome, a condition that may increase your sensitivity to hormone-based treatments.
How to Store Wegovy?
Wegovy should be stored in the refrigerator between 36°F and 46°F (2°C to 8°C), and it's important not to freeze it. Frozen pens should be discarded. If needed, the pen can be kept at room temperature (up to 86°F or 30°C) for up to 28 days, but after that, it must be thrown away, even if unused.
If you’re wondering how should I store my Wegovy® injections? Well, it’s best to keep the pen in its original carton to protect it from light and avoid shaking it, as this can damage the medication. Store Wegovy safely out of reach of children and pets, and use a sharps disposal container for safe disposal after use.
When To Seek Support While Using Wegovy?
If you experience side effects, don’t panic. Many are common and often improve as your body adjusts. Nausea, sore throat, diarrhoea, stomach flu, or headache are the most common side effects. To manage these:
- Stay hydrated and eat bland, smaller meals if you feel nauseous.
- Avoid fatty or spicy foods, which can cause upset stomach or worsen digestive symptoms.
- Talk to your doctor before stopping Wegovy. They may adjust your dose or suggest ways to ease symptoms.
- Report serious side effects such as severe abdominal pain, vision changes, thoughts of suicide or signs of an allergic reaction immediately.
Always consult your healthcare provider if you're unsure whether a symptom is normal or needs medical attention.
Looking for a Simple Way to Start Wegovy? DooÜ Can Help
Managing your Wegovy treatment should be simple, supportive, and stress-free. That's exactly what DooÜ offers with trusted care delivered straight to your door.
Here's what you can expect:
- A quick, secure online medical assessment
- Prescriptions approved by licensed Canadian doctors
- Free, discreet delivery anywhere in Canada
- Direct insurance billing to reduce out-of-pocket costs
- Ongoing support to guide you through every dose
From your first injection to dose adjustments, DooÜ makes staying on track easier than ever.
Have questions about starting Wegovy?
Final Words
Starting Wegovy injections might feel unfamiliar at first, but with a little practice, it becomes part of your routine. Everyone’s experience is different, so be patient and give yourself time to adjust. If any questions or concerns come up, your healthcare provider is the best person to guide you.
Remember, weight management is a gradual process. Taking it step by step and staying consistent can lead to meaningful results over time. Keep focused on your goals. You're making progress every week.
Frequently Asked Questions
What is Wegovy® and why is it injected into the thigh?
Wegovy® is a prescription medication that contains Semaglutide. It’s injected into the fatty tissue just under the skin (subcutaneously). The thigh is one of the recommended sites because it’s easy to access and absorbs the medication effectively. But you can also inject Wegovy in your upper leg or even lower stomach.
Are there alternatives to injecting Wegovy® into the thigh?
Yes, you can also inject Wegovy® into your abdomen or upper arm at any time of day. According to Novo Nordisk website, all three sites are equally effective, so you can choose the one that feels most comfortable or fits your routine best. Just remember to rotate your injection spot each week.
Is it better to inject Wegovy in the morning or at night?
There’s no medically preferred time to inject Wegovy®. You can take it mornings or nights, whatever fits best with your schedule. Just stay consistent each week. Some people prefer evening doses of Wegovy to sleep through any mild side effects like nausea.
Does it hurt to inject Wegovy?
Most people feel only mild discomfort or a quick pinch. The small needle injects just under the skin, not into the muscle, making it gentler than many other shots. Some slight pressure or tenderness may occur, but usually fades quickly.
What should I do if my Wegovy pen malfunctions?
If your Wegovy pen doesn’t work properly or stops before delivering the full dose, don’t reuse it or take an extra dose. Contact Wegovy support at 1-833-4-WEGOVY for help and possible replacement. You can also reach out to DooÜ or your healthcare provider for guidance, especially if you have specific health concerns.
Is it possible to inject Wegovy wrong?
Yes, it’s possible if the pen isn’t pressed properly, injected into muscle, or removed too soon. Always follow the instructions carefully and ensure the yellow bar fully moves before lifting the pen. If unsure, contact your provider or Wegovy support, especially if you experience mild symptoms like a runny nose or severe stomach problems, or have symptoms of thyroid cancer or any endocrine system condition.
Who should not use Wegovy?
Wegovy should only be used under medical supervision. If you have any concerns about whether it’s appropriate for you, consult your healthcare provider, who can determine suitability based on your personal health history.
Can you inject Wegovy cold?
Yes, Wegovy can be injected cold and should be stored in the refrigerator between 2°C and 8°C. However, injecting it cold may cause discomfort or stinging. For a more comfortable experience, let the pen sit at room temperature for about 30 minutes before use. Never freeze the pen or try to heat it up.
Is it safe to use Wegovy if I need deep sedation?
Tell your healthcare team if you use Wegovy before any procedure with deep sedation. It may affect blood sugar, so your doctors might need to monitor or adjust your treatment for safety.
How to use Wegovy injection pens and dosage forms?
To use it, it is advisable to discuss all the important safety information with a health care professional. Press the pen firmly against the skin at a 90-degree angle and hold until the yellow bar stops moving. Never reuse or share pens.
What are the adverse effects?
The medication can lead to nausea, vomiting, diarrhoea, constipation, stomach pain, and fatigue. More serious risks include medullary thyroid carcinoma (a type of thyroid cancer), endocrine neoplasia syndrome type 2, worsening diabetic retinopathy, and rare suicidal thoughts, especially in individuals under 25 years of age taking it for weight loss.
Disclaimer:
This content is provided for general educational purposes only and should not be interpreted as medical advice. Wegovy and other prescription medications should only be used under the guidance of a licensed healthcare professional. Always consult your doctor, pharmacist, or another qualified healthcare provider before making decisions about your health, treatment, or medications.















































