If you're reading this, chances are you’ve been battling with weight loss for a while. You’ve tried the diets, the workouts, and the countless "miracle" methods, yet the scale doesn’t seem to budge. So, what if there was something more to support you on your journey?
Weight loss pills have become a popular solution for many Canadians, offering a bit of extra help when the typical approaches aren't enough. However, with numerous options available on the market, it's challenging to determine which ones are genuinely worth trying.
In this blog, we’ll break down the most effective weight loss pills available in Canada, showing you not just which ones work but why they might be the right fit for your goals. If you're frustrated and wondering where to start, this guide will provide a clearer understanding of your options, enabling you to make an informed decision and feel more confident in your weight loss journey.
Best Weight Loss Pills that Work in Canada
In Canada, prescription weight loss pills like Contrave and Orlistat offer significant results for those struggling with obesity. However, these medications come with both promise and risk, and understanding their effects is crucial before committing.
1. Contrave: The Dual-Action Appetite Control
Contrave combines Naltrexone and Bupropion, two medications that target the brain's reward center, reducing cravings and helping you eat less. This combination results in a significant reduction in appetite, enabling you to adhere more closely to your diet and exercise plan. In clinical trials, 66% of participants lost more than 5% of their body weight, with 29% shedding over 15% of their body weight.
However, the most common side effects, like nausea, dizziness, and headaches, are common, making this treatment best suited for individuals with a BMI of 30 or higher or a BMI of 27 with weight-related health issues.
While starting your weight loss journey with Contrave could be a challenge for some, it never has to be now with DooÜ, a trusted provider of personalized weight loss solutions. You can now skip the blood tests and enjoy the convenience of free delivery and direct insurance billing with us. Right after assessing you, our doctors will create a plan tailored to your health goals. Want to know how it works? Check out our Contrave page and get started!
2. Orlistat (Xenical): Fat Absorption Blocker
Orlistat works by blocking the absorption of dietary fat, preventing up to 30% of fat from being absorbed by your body.
While effective, it’s crucial to stick to a low-fat diet, as consuming high-fat meals can lead to uncomfortable side effects, such as oily stools and gas.
While a 5% weight loss is typical within the first six months, it's essential to take a daily multivitamin to prevent deficiencies in fat-soluble vitamins. Orlistat is ideal for people with a BMI over 30 or 27 with comorbid conditions, but it requires strict diet control for best results.

Injectable Weight Loss Medications: Exploring the Best Options Available
When it comes to weight loss, injectable medications have become a popular choice, offering both practical results and the convenience of medical oversight. From Ozempic to the newer Mounjaro and Zepbound, let’s explore how these treatments work, their benefits, and what you should know before choosing one.
1. Ozempic (Semaglutide)
Although approved initially for managing Type 2 diabetes, Ozempic (semaglutide) has become a go-to weight loss aid for many individuals. By mimicking the GLP-1 hormone, it helps control blood sugar levels, reduce hunger, and slow digestion, allowing people to eat less and feel fuller for longer.
For those aiming to shed pounds, Ozempic has shown impressive results, helping users get an average weight loss of 5-10% of their initial body weight over approximately 68 weeks. Its once-weekly injection makes it a convenient and long-term solution for weight management.
But you should know how to use it properly, as it has its own side effects, including vomiting, diarrhea, stomach pain, low blood sugar, dehydration, thyroid tumors, and the "Ozempic face."
Ready to start your weight loss journey with Ozempic? DooÜ makes it easy to get started with free delivery, direct insurance billing, and personalized support from Canadian doctors. With DooÜ, you can have Ozempic delivered right to your door and begin managing your weight on your terms. Visit our Ozempic page to learn more and start your weight loss journey.
2. Wegovy (Semaglutide)
While Wegovy also contains semaglutide, it’s specifically designed for weight loss. Similar to Ozempic, Wegovy works by controlling appetite and slowing gastric emptying, but with a higher dose tailored to promote greater weight loss.
Common side effects of Wegovy include nausea, vomiting, diarrhea, stomach pain, constipation, headache, fatigue, and low blood sugar. In rare cases, it may also cause thyroid tumors or gallbladder problems.
In clinical trials, patients have lost an average of 10% of their body weight within six months, making Wegovy an ideal option for those seeking to lose a substantial amount of weight. It's a convenient once-weekly injection and is approved for adults with a BMI of 30 or higher or 27 with related health issues like hypertension or diabetes.
3. Saxenda (Liraglutide)
For those who prefer a daily regimen, Saxenda (liraglutide) offers a strong weight-loss solution. Like Ozempic and Wegovy, Saxenda is a GLP-1 receptor agonist, but it requires daily self-injections. It works by slowing the digestion process and signalling fullness, helping reduce hunger and cravings.
Common side effects of Saxenda (liraglutide) include nausea, vomiting, diarrhea, constipation, stomach pain, headache, and fatigue. Rare side effects may include low blood sugar, gallbladder issues, and thyroid tumors.
In clinical t rials, 64% of patients lost at least 5% of their body weight during the year. Though it requires daily injections, Saxenda’s established track record makes it a popular choice for those committed to consistent weight management.
4. Mounjaro (Tirzepatide)
A relatively new contender in the weight loss medication arena, Mounjaro (tirzepatide) offers a dual-action approach by targeting both the GLP-1 and GIP (gastric inhibitory polypeptide) receptors, making it more effective at reducing appetite and promoting fat burning.
Common side effects of Mounjaro (tirzepatide) include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. Rare but serious side effects may include low blood sugar, gallbladder issues, and thyroid tumors. Some users may also experience dehydration due to gastrointestinal symptoms.
In clinical studies, Mounjaro has shown even greater potential than semaglutide, with users losing up to 20.2% of their body weight over time. As a weekly injection, it’s fast becoming a top choice for individuals seeking more powerful results in their weight loss journey.
5. Zepbound (Tirzepatide)
Zepbound, another tirzepatide medication, has shown promise for both weight loss and blood sugar control, though it is still awaiting approval from Health Canada. Like Mounjaro, it targets two hormones to enhance satiety and fat loss. This dual action makes Zepbound an effective solution for individuals managing Type 2 diabetes and looking to lose weight at the same time.
Common side effects of Zepbound (tirzepatide) include nausea, vomiting, diarrhea, stomach pain, and decreased appetite. Rare side effects may include low blood sugar, gallbladder issues, and thyroid tumors.
It’s gaining traction for its ability to support significant weight loss; some users have experienced reductions of up to 20% of their body weight.
Whether you're starting with Ozempic, Wegovy, Saxenda, Mounjaro, or Zepbound, DooÜ makes it easy to get the weight loss treatment you need. Enjoy free delivery, direct insurance billing, and personalized support from us at the best price.

Can You Maintain Your Weight Loss After Stopping Weight Loss Pills?
Weight regain is a common challenge after stopping weight loss medications. Many people experience the return of hunger and changes in metabolism, leading to the regaining of up to two-thirds of the weight lost within a year. This is particularly true for those who initially lost a significant amount of weight.
However, lifestyle changes such as maintaining regular exercise and making smarter dietary choices can help sustain fat loss after discontinuing medication. Collaborating with your healthcare provider to create a long-term weight management plan can also help you avoid relying on drugs and support lasting results.
Remember, weight management is a lifelong journey, and achieving successful long-term weight loss requires consistency, not just quick fixes.
How to Find the Best Weight Loss Medication for You?
Choosing the proper weight loss medication requires consideration of factors like your BMI, lifestyle, and potential side effects. It’s essential to consult with your healthcare provider to ensure the option you choose aligns with your medical history and health goals.
Here’s a quick comparison of popular weight loss medications:
Your Weight Loss, Your Way with DooÜ
Achieving weight loss goals doesn’t have to be a solo journey. With Dooü, you receive personalized support, expert advice, and effective treatments, such as Ozempic and Wegovy, delivered directly to your door. Our expert doctors tailor your plan to meet your specific needs, ensuring you receive the proper support every step of the way.
Ready to take the first step? With a simple 5-minute intro, you’ll have a plan in place in 24 hours: no blood tests, no hassle, just tailored weight loss solutions that fit your lifestyle. Don’t wait to start living your healthiest life.
Your Path to Effective Weight Loss
Choosing the proper weight loss medication is crucial for long-term success. All of the above-mentioned medications are proven to help reduce starting weight, improve diabetes control, and lower blood pressure. However, these medications work best when combined with exercise, a balanced diet, and regular health monitoring.
It's essential to consult with a healthcare provider to understand how these drugs impact your digestive system and pancreas, as well as potential side effects like constipation and nausea.
Before starting treatment, assess your body mass index (BMI) and discuss insurance plans to ensure complete coverage. With the right weight loss strategy, you can manage obesity, reduce serious health problems like heart disease and high cholesterol, and enhance your overall health and quality of life for lasting results.
Frequently Asked Questions
What is the most effective weight loss pill available in Canada?
According to the FDA, Wegovy, which is based on semaglutide, is one of the most effective weight loss medications in Canada. Clinical trials show people lose about 15% of their fat when using it. Other well-known tablet options are Contrave and Orlistat. These tablets also aid in weight loss, particularly when combined with lifestyle changes and under a doctor's supervision. Their efficacy is better when people make these changes and follow their doctor’s advice.
Are weight loss pills Canada safe for long-term use?
Some prescription weight loss pills like Orlistat and Contrave can be safe to use for a long time, as long as your healthcare providers keep an eye on you. But these pills can cause common side effects, including nausea, and can upset your stomach, which may make it hard for some people to keep using them. If you plan to use these medicines for a long time, the plan should align with your treatment plan, health, and what you and your doctor think is best.
Do you need a prescription for all weight loss pills in Canada?
Not all weight loss pills require a prescription. You can get Orlistat as a prescription drug called Xenical. Alternatively, you can purchase its over-the-counter version, named Alli. Some other choices, like Contrave, still need a prescription from your doctor. There are also supplements and weight loss inhibitors that you can purchase at the store or online without a prescription. However, the FDA does not regulate most of these. You should use these with care.
Can weight loss pills be used in conjunction with other medications?
The best weight loss capsules, such as Contrave, can mix with other drugs like antidepressants and enzyme inhibitors. You need to adjust your dosage under a doctor's supervision to minimize the risk of adverse side effects. Always talk to your healthcare provider before taking different medicines together to ensure they are safe and work well for you.
Who should avoid using weight loss pills?
People who have serious health issues, such as high blood pressure that is not under control, a quick heart rate, or pancreatitis, should not take weight loss medications. If you are pregnant or have trouble with stimulants, you should also avoid these drugs. Healthcare providers decide if weight loss medications are right for you by looking at your medical history and any long-term health problems you have.